Douglas Weber is broadly interested in understanding the role of sensory feedback in supporting and regulating a wide range of perceptual, motor, cognitive, and autonomic functions. His research combines fundamental neuroscience and engineering research to understand physiological mechanisms underlying sensory perception, feedback control of movement, and neuroplasticity in sensorimotor systems. Knowledge gained from these studies is being applied to invent new technologies and therapies for enhancing sensory and motor functions after stroke, spinal cord injury, or limb loss. These principles are also being applied to develop wearable devices for enhancing sensory, motor, and cognitive functions in healthy humans. He is committed to transitioning outputs of his academic research into practical technologies that support real-world applications, and he works actively with industrial partners to bridge the gap from bench to market.

A founding member of DARPA’s Biological Technologies Office, Weber created and managed a portfolio of neurotechnology research programs to support the White House BRAIN initiative, launched by President Obama in 2013. He created DARPA’s HAPTIX, ElectRx, and TNT programs, which are developing implantable, injectable, and wearable neurotechnologies that restore natural motor and sensory functions for amputees, enable novel and drug-free therapies for treating inflammatory disease and mental health disorders, and promote plasticity in the brain to enhance learning of complex cognitive skills.

Weber completed post-doctoral training in the Centre for Neuroscience at the University of Alberta. He holds eight issued United States patents and has published extensively on a wide range of topics spanning sensorimotor neurophysiology, biomechanics, neural engineering, and physical medicine. He has mentored over 100 undergraduate, graduate and medical students and several post-doctoral fellows.

1323 Wean Hall
Google Scholar
Douglas Weber

Improving the Interface Between Humans and Machines


2001 Ph.D., Bioengineering, Arizona State University

2000 MS, Bioengineering, Arizona State University

1994 BS, Biomedical Engineering, Milwaukee School of Engineering

Media mentions


CMU and collaborators awarded NIH grant

In collaboration with CMU, UPMC, and the Mount Sinai Health System, Synchron received a $10 million National Institutes of Health grant to begin a trial of their brain-computer interface, reports FierceBiotech, BioSpace, Medical Device Network, and Mobi Health News.

CMU Engineering

Sense and signal

A novel brain-computer interface will allow the severely paralyzed to send email messages and perform daily tasks like online shopping and banking with their minds.

CMU Engineering

Resetting travelers’ circadian clocks

Carnegie Mellon researchers are working with DARPA, Northwestern University, and Rice University to develop a system for regulating the body’s circadian clock.

IEEE Spectrum

Weber’s research video featured

MechE’s Doug Weber’s faculty research video was featured by IEEE Spectrum’s “Your weekly selection of awesome robot videos.”

Engineering faculty awarded professorships

Engineering faculty Peter Adams, Elizabeth Dickey, Carlee Joe-Wong, Pulkit Grover, Alan McGaughey, Rahul Panat, and Douglas Weber were awarded professorship titles in February and March 2021.

Mechanical Engineering

The fusion of human and machine

New faculty member Doug Weber is combining engineering and neuroscience research to solve challenges related to control and sensation in humans and robotics.


Weber’s brain research featured

MechE’s Doug Weber’s research on using the brain to control computers was featured in Wired.

Behind the Bench

Weber featured in Behind the Bench

Behind the Bench featured MechE’s Doug Weber in an extensive piece about his career and research.

CMU Engineering

Wearable system to sense and stimulate the brain

A team of researchers from Carnegie Mellon is starting a project to design and implement a high-resolution, noninvasive neural interface that can be used as a wearable device.

University of Pittsburgh Swanson School of Engineering

Weber featured for brain-computer interface technology

MechE’s Doug Weber was featured by the Swanson School of Engineering at Pitt for his work in brain-computer interface (BCI) research that allows paralyzed individuals to connect mind to machine and control robotic devices with their brains, work funded by DARPA.